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GPCR drug discovery Jana Selent

Publications 2026 (5)

• Aldasoro V^*, Laiño M, Enguita M, Loricera J, Moriano C, Lasa C, Calvo V, Narváez FJ, Navarro P, Casafont I, Font J, Gallego A, Carrión I, Quiroga P, Castañeda S, Garcia A, Belzunegui J, López M, de Dios JR, Hernández S, Heredia S, Fariña A, Navarro F, Fragio J, Escudero C, Ortega R, Olmo LD, Pinillos V, Labrador E, Ortega MC, Castro P, Blanco J, Paulino M, Matías MÁ, Peralta C, Garcia S, Camins J, Garijo M, Fábregas D, Urruticoechea A, Medina M, Cossio P, Pérez-Pampín E, Varas B, Vazquez C, Balsalobre J, Vegas N, Rusinovich O, Giner E, Lamúa JR, Abascal IB, Moreno MJ, Perez P. Spanish multicenter registry of belimumab in systemic lupus erythematosus: Data from daily clinical practice. Semin Arthritis Rheu 2026; 79: .
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• Steiner WP, Iverson N, Liu G, Venkatakrishnan V, Wu J, Stepniewsk TM, Michaelson Z, Bröckel JW, Zhu JF, Bruystens JGH, Lee A, Nelson I, Bertinetti D, Arveseth CD, Tan G, Spaltenstein P, Xu J, Hüttenhain R, Kay MS, Herberg FW, Cao E, Selent J, Anand GS, Dunbrack JR RL^*, Taylor SS, Myers BR. Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway. Nat Struct Mol Biol 2026; 33(5): 795-809.
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• Tiwari D, Sawada K, Dalal A, Mishra S, Li XX, Dent JC, Kim K, Yadav MK, Roy N, Ganguly M, Banerjee N, Stepniewski TM, Ahn D, Yamaguchi K, Oshima HS, Hashimoto K, Fung JN, Lerskiatiphanich T, Cui CS, Lee JD, Selent J, Inoue A, Clark RJ, Chung KY, Banerjee R, Sano FK, Woodruff TM, Nureki O, Shukla AK^*. Molecular mechanisms of naturally encoded signaling bias at the complement anaphylatoxin receptors. Mol Cell 2026; 86(13): 2586-2604.
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• Balfe EM, Torbey A, Stepniewski TM, Zhou Y, Kohlenbach L, Sency JA, Inoue A, Slosky LM, Selent J, Barak LS, Gross JD^*. Rare variant in intracellular loop-2 alters the spatial distribution and transducer coupling selectivity of the ghrelin receptor. Mol Pharmacol 2026; 108(4): 100119.
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• Medel-Lacruz B. Enhancing Early-Stage Drug Discovery through Biophysical Approaches. Universitat Pompeu Fabra. Director: Selent J. Fecha lectura: 12/01/2026.
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