Anna Bigas co-leads a new project on T-cell Acute Lymphoblastic Leukaemia, funded by the Deutsche José Carreras Leukämie Stiftung

11/06/2026

A new project investigating the mechanisms of chemotherapy resistance in T-cell acute lymphoblastic leukaemia (T-ALL) receives funding from the Deutsche José Carreras Leukämie Stiftung. The study is co-led by Dr Anna Bigas, Group Leader at the Hospital del Mar Research Institute and the Josep Carreras Leukaemia Research Institute, and Professor Christoph Plass of the German Cancer Research Center.

T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy that affects both children and adults. Although current treatment regimens achieve remission in a high proportion of patients, resistance to chemotherapy remains the leading cause of relapse and is associated with poor clinical outcomes. Understanding the biological mechanisms that enable certain leukaemic cells to survive treatment is therefore a major unmet medical need and essential for the development of new therapeutic strategies.

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