14/06/2018 - General information
On the 18th and until the 20th, the PRBB Consortium will replace all of the current phones of the IMIM for IP telephones with more features. During this change process there will be times when external and /or internal telephone connections will not work. We recommend that you communicate, whenever possible, via email.
Més informació "IMPORTANT: Telephone connection cuts from June 18 to update the system"
17/05/2018 - Institutional news
The two IMIM researchers, Lluís Espinosa and Anna Vert, have been chosen to edit a special edition of the journal Biomedicines, from the MDPI publishing house. Under the title Stem Cells and Cancer Therapeutics, it will focus, in the words of the publishers, "on understanding the molecular mechanisms controlling normal cells and stem cells related to cancer, as well as the tools available for studying them in vitro and in vivo." This issue will focus on how new technologies can be used in cancer therapies. The special edition will include around twelve articles by particularly renowned authors. Five of these articles can already be consulted in open format, including the paper "Mammary Stem Cells and Breast Cancer Stem Cells: Molecular Connections and Clinical Implications", authored by Dr. Toni Celià-Terrassa, a researcher from the IMIM's Cancer Research Programme.
19/04/2018 - Institutional news
The 3rd European Conference on Translational Bioinformatics (ECTB2018) was held on April 16th-17th at the premises of the Barcelona Biomedical Research Park (PRBB) with the attendance of more than 130 European scientists, developers, and entrepreneurs, interested in translating genomics and bioinformatics research into healthcare tools and services. The conference aimed to give the participants a unique experience and a forum for discussing fresh scientific results in the translational domain. The conference brought together world-leading scientists in the area which highlighted on their presentations the recent advances in information technologies that are facilitating translational research and precision medicine. Some of the topics addressed were Big Data integration and analysis, Personalized Medicine, Genome Sequencing initiatives, etc, delivered by scientists from Europe, Canada and the USA.
19/03/2018 - Press release
Dr. Rafael de la Torre, director of the Neurosciences research programme at the Hospital del Mar Medical Research Institute (IMIM), is leading a clinical trial involving a paediatric population, the aim of which is to evaluate the safety and effectiveness of a dietary preparation containing epigallocatechin gallate (EGCG) – a natural compound found in green tea- on improved cognitive development in children, aged 6 to 12, with Down's syndrome, and which will also evaluate its effect on children with Fragile X syndrome. The paediatric clinical trials will take place simultaneously in 5 health centres: Hospital Niño Jesús (Madrid), Instituto Hispalense de Pediatria (Seville), Hospital Universitario Marqués de Valdecilla (Santander), Hospital del Mar ( Barcelona), and Institut Jérome Lejeune (Paris).
06/03/2018 - Press release
The Evolutionary Genomics research group at the IMIM, led by Mar Albà, has just published an article in the journal Molecular Ecology providing the results of a study that has identified which genes participate (change their expression) in the hibernation state of hairy-eared dwarf lemurs, which belong to the only group of primates that has the ability to hibernate. These small mammals store fats in their tails, allowing them to survive the months of shortage, and which they use as fuel during hibernation. Hibernation is a response to the lack of resources we normally associate with winter, but which can occur in other conditions of scarcity, such as in desert areas or, for example, during the dry season in Madagascar. “The genes involved in hibernation are present in almost all mammals, including humans. It is a question of when and how they are expressed that makes the phenomenon of hibernation possible. As they are primates, lemur genes are relatively similar to those in humans, so it is even more interesting to study this species”, explains José Luis Villanueva-Cañas, a researcher from the IMIM's Evolutionary Genomics group.
Més informació "First genetic study of primate hibernation in their natural environment"
23/01/2018 - Press release
The director of the Epidemiology and Public Health programme at the Hospital del Mar Medical Research Institute (IMIM) and CIBER Epidemiology and Public Health (CIBERESP) researcher, Jordi Alonso, was commissioned by the World Mental Health to lead an international study into the adequacy of anxiety disorder treatment across the globe. The results, from a sample of more than 51,500 individuals from 21 different countries, reveals that 10% of people suffer anxiety. Of these, only 27.6% have received some type of treatment, and this was considered appropriate in only 9.8% of the cases. It is the first time a study has described the treatment gap in anxiety disorders at an international level. "It is estimated that anxiety disorders affect 10% of the global population. These are pathologies that tend to be chronic, comorbid, and associated with a significant disability. If we add to this the fact that in 2010 they cost a group of 30 European Union countries €74,400 million, it is clear that this is an important public health problem", explains Jordi Alonso.
16/01/2018 - Press release
Being overweight or obese exponentially increases the risk of suffering heart disease or cancer. This is the conclusion of the FRESCO (Spanish Risk Function of Coronary and Other Events) study, led by researchers from the Hospital del Mar Medical Research Institute (IMIM) and doctors from Hospital del Mar, who analysed the follow up of 54,446 people from 7 autonomic communities over a ten-year period. The work involved various research groups from Barcelona, Girona, Reus, Palma de Mallorca, Zaragoza, Murcia, Pamplona, Seville, and Talavera de la Reina. The results of the study are clear. The obesity epidemic has a greater impact on women. In fact, women are 5 five times more likely to suffer a cardiovascular disease, and have 12 times greater risk of developing cancer than those of normal weight, Being overweight, even if this does not reach obesity levels, still involves twice the risk of heart disease and four times the risk of cancer.
Més informació "Obesity and overweight multiply the risk of suffering cancer and heart disease"
15-01-2018 - General information
The Food and Drug Administration's Center for Drug Evaluation and Research (FDA/CDER) and Chemotargets will work together under a 5-year Research Collaboration Agreement (RCA). The primary objective of the research agreement will be to assess the utility and performance of the Chemotargets CLARITY® intelligence & discovery platform to predict on-target and off-target activities using known pharmacology and safety data from experimental studies of small molecular entities. Evaluating in silico models for broad pharmacological profiling is of interest to CDER to predict potential adverse events of drugs in development. Additionally, insight into a chemical’s molecular target profile can help predict abuse and addiction potential, which may reduce risks associated with exposure to these substances.
18/12/2017 - Institutional news
Gasol Foundation, set up by NBA players Pau and Marc Gasol, and the Hospital del Mar Medical Research Institute (IMIM) have signed an agreement to develop joint research projects. The aim of this accord is to establish a collaboration framework between the organisations with regard to biotech research and development in the field of childhood obesity. This will allow them to work together to gain competitive funding and publicise the results of their joint projects. The agreement will promote the cross-training of staff from the two entities, and the IMIM team will provide methodological support in the design and development of the Gasol Foundation's public health interventions, as well as in the analysis and dissemination of the data they obtain. A task that will be carried out by the IMIM's Cardiovascular Risk and Nutrition research group.
04/12/2017 - Press release
What distinguishes Homo sapiens from other living beings? And the group of mammals? What makes them different? These are the questions that researchers from the Hospital del Mar Medical Research Institute (IMIM) have been trying to answer, together with the Department of Experimental and Health Sciences at the Pompeu Fabra University (UPF). To do this, they analysed the already-sequenced genomes of 68 mammals and identified 6,000 families of genes that are only found in these animals. These are genes with no homologues outside mammals, in other words, they are not present in other hairless species. In humans, it is estimated that they represent 2.5% of the genes that code for proteins. The work was led by Dr. José Luis Villanueva-Cañas, a member of the IMIM's Evolutionary Genomics research group, and currently a researcher at the Evolutionary Biology Institute (UPF-CSIC), and Dr. Mar Albà, an ICREA researcher at both the IMIM and the Biomedical Informatics Research Programme (GRIB). The study also involved Dr. David Andreu's group from the UPF's Department of Experimental and Health Sciences. It has been published in the journal Genome Biology and Evolution.
Més informació "Genes identified that distinguish mammals from other animals"
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