11/04/25 - Institutional news
Dr. Jenniffer Linares, a researcher with the Colorectal Cancer Precision Medicine Research Group at the Hospital del Mar Research Institute, has received the CRIS Program for Translational Medical Talent, awarded by the CRIS Against Cancer Foundation. A total of 11 million euros in funding has been granted through the CRIS Research Programs 2024, with the aim of promoting cancer research that places the patient at the center of scientific advancement. The awarded project, "Uncovering the Clinical Impact of Stromal-Derived Mechanisms of Resistance to Anti-EGFR Therapy in Colorectal Cancer," seeks to understand the mechanisms of resistance to anti-EGFR therapies derived from the tumor microenvironment in patients with RAS wild-type metastatic colorectal cancer. The goal is to identify predictive markers and develop new therapeutic strategies to overcome these mechanisms. The project will receive funding of 400,000 euros.
Més informació "CRIS Against Cancer Awards Dr. Jenniffer Linares"
10/04/2025 - Institutional news
This initiative, aimed at supporting people with mild to moderate depression, is being relaunched with new and improved features. The goal is to enhance both user experience and accessibility. The project is an initiative of the European Alliance Against Depression (EAAD), in collaboration with the Mental Health area of CIBER (CIBERSAM), and led by the Hospital del Mar Research Institute.
09/04/2025 - Press release
A study involving more than 1,700 people from five hospitals in Barcelona, Sweden and Italy has validated the usefulness of a biomarker in blood to detect Alzheimer's disease in the clinical setting. The study, published in the journal Nature Medicine, demonstrates that this test can be a useful and applicable tool in routine medical practice. The automated analysis of this biomarker is more than 90% effective in identifying patients with Alzheimer's disease. It is an easy-to-use tool that can partly replace other, more complex diagnostic tests, such as lumbar puncture or positron emission tomography (PET). The study has established cut-off points from which the patient's symptoms can be considered to be caused by Alzheimer's, if Alzheimer's disease can be ruled out, or if further tests are needed to determine the cause of the disease.
Més informació "A blood test for early detection of Alzheimer's disease"
04/04/25 - Institutional news
The Scientific Foundation of the Spanish Association Against Cancer has just named the accredited centres under the AECC Scientific Foundation Accreditation 2024, among them, the Hospital del Mar Research Institute. In total, there are 13 centres of excellence in cancer research that receive this recognition. With this initiative, the Scientific Foundation aims to promote coordination and collaboration between the centres and the organisation, as well as achieve more efficient management of funds and maximise their impact. To adhere to the accreditation, the research institute had to undergo a thorough evaluation process, in which it was verified that it meets the requirements to join the accreditation. In this regard, it was certified that the institute has at least two active project grants awarded by the AECC in the last three years. Also, to have three principal investigators in cancer research, have an ongoing international cancer project or have published two articles in this field as last authors in a high-impact peer-reviewed journal. Finally, to have a defined cancer research strategy with specific lines and periodic action plans.
31/03/25 - General information
People with bronchiectasis, a chronic airway disease characterized by the accumulation of secretions in the bronchi leading to recurrent lung infections, are at high risk of experiencing a decline in muscle mass and function, known as sarcopenia. Having tools to diagnose their condition is vital to slowing its progression and avoiding a point of no return. For this reason, the Muscle Wasting and Cachexia in Chronic Respiratory Diseases and Lung Cancer Research Group of the Hospital del Mar Research Institute, together with the Pneumology and Radiology Services of Hospital del Mar and part of the dibi network, have conducted a study to validate the use of magnetic resonance imaging (MRI) to assess the muscular condition of these patients. The study is published in Archivos de Bronconeumología and also includes researchers from the CIBER Respiratory Diseases area (CIBERES).
27/03/2025 - Press release
Previously unknown access points in cell membrane proteins have been discovered, enabling laboratory-developed drugs to modify cell function. The discovery was made possible through computer simulations with an unprecedented level of detail. The results are available online to support the development of new, targeted drugs for a wide range of diseases. Research centers from thirteen countries collaborated on the study, which has been published in Nature Communications.
Més informació "New pathways discovered for drugs to act on cells"
25/03/2025 - General information
A new study led by researchers from the Hospital del Mar Research Institute and the Barcelonaβeta Brain Research Center (BBRC), the research centre of the Pasqual Maragall Foundation, has made significant strides in the search for effective blood-based biomarkers for Alzheimer's disease early detection. The research, published in the journal Alzheimer's & Dementia, provides a comprehensive comparison of various plasma biomarkers and their accuracy in detecting Alzheimer's disease in a memory clinic setting.
24/03/2025 - Press release
The genetic modification of the Natural Killer (NK) cells, lymphocytes forming part of the body's immune system, would make it possible to retain their capacity of eliminating tumour cells in solid tumours. Some types of tumours secrete two molecules, TGF-β and Activin A, which supress the capacity of NK cells to attack them. A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells to make them immune to the tumour's defense mechanism.
Més informació "New tool to boost cancer immunotherapy effects"
21/03/2025 - Press release
Coinciding with the celebration of World Down Syndrome Day, the results of the GODS21 study, a pioneering initiative on the relationship between obesity and people with Down syndrome, have been presented. A healthy diet is associated with higher IQ scores in this population. The GODS21 study (Gene Overdosage and Comorbidities During the Early Lifetime in Down Syndrome) has revealed the importance of nutrition in cognitive development for individuals with Down syndrome. These findings were presented on March 21, marking World Down Syndrome Day. The study has analyzed the link between obesity and Down syndrome, highlighting the need to consider nutrition as a key factor in improving health.
Més informació "The Importance of Nutrition in People with Down Syndrome"
17/03/2025 - General information
The BAPP, a joint center between the Hospital del Mar Research Institute and Pompeu Fabra University, will maintain this quality seal from the Government of Catalonia until 2028. This recognition highlights its scientific and technical excellence, as well as its capacity for knowledge and technology transfer to the industry. The BioAnalysis, Proteomics and Pharmacology Center (BAPP), part of the Hospital del Mar Research Institute and Pompeu Fabra University, has renewed its TECNIO accreditation, awarded by the Government of Catalonia through ACCIÓ. This accreditation, valid until 2028, identifies and gives visibility to highly capable scientific and technical centers, recognized as developers of cutting-edge technologies and leaders in technology and knowledge transfer to the industry.
Més informació "The Hospital del Mar Research Institute renews the TECNIO accreditation"
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